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1

Design and Evaluation of Pilicides: Potential Novel Antibacterial Agents Directed Against Uropathogenic Escherichia coli

Anette Svensson, Andreas Larsson, Hans Emtenäs, Mattias Hedenström, Tomas Fex, Scott J. Hultgren, Jerome S. Pinkner, Fredrik Almqvist, Jan Kihlberg

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 144 KB

english, 2001

2

ChemInform Abstract: Design and Evaluation of Pilicides: Potential Novel Antibacterial Agents Directed Against Uropathogenic Escherichia coli.

Anette Svensson, Andreas Larsson, Hans Emtenaes, Mattias Hedenstroem, Tomas Fex, Scott J. Hultgren, Jerome S. Pinkner, Fredrik Almqvist, Jan Kihlberg

Journal:

Année:

2002

Fichier:

PDF, 24 KB

2002

3

Toward high-throughput drug screening on a chip-based parallel affinity separation platform

Sten Ohlson, Minh-Dao Duong-Thi, Maria Bergström, Tomas Fex, Lennart Hansson, Lennart Pedersen, Sergio Guazotti, Roland Isaksson

Journal:

Journal of Separation Science

Année:

2010

Langue:

english

Fichier:

PDF, 253 KB

english, 2010

4

Use of 19F NMR spectroscopy to evaluate reactions in solid phase organic synthesis

Anette Svensson, Tomas Fex, Jan Kihlberg

Journal:

Tetrahedron Letters

Année:

1996

Langue:

english

Fichier:

PDF, 222 KB

english, 1996

5

Screening for transient biological interactions as applied to albumin ligands: A new concept for drug discovery

Sten Ohlson, Siamak Shoravi, Tomas Fex, Roland Isaksson

Journal:

Analytical Biochemistry

Année:

2006

Langue:

english

Fichier:

PDF, 306 KB

english, 2006

6

Weak affinity chromatography as a new approach for fragment screening in drug discovery

Minh-Dao Duong-Thi, Elinor Meiby, Maria Bergström, Tomas Fex, Roland Isaksson, Sten Ohlson

Journal:

Analytical Biochemistry

Année:

2011

Langue:

english

Fichier:

PDF, 1.39 MB

english, 2011

7

Design and synthesis of macrocyclic indoles targeting blood coagulation cascade Factor XIa

Stephen Hanessian, Andreas Larsson, Tomas Fex, Wolfgang Knecht, Niklas Blomberg

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2010

Langue:

english

Fichier:

PDF, 619 KB

english, 2010

8

Chalmicrin, a mannitol ether of methylated monocyclofarnesol, from Chalara microspora

Journal:

Année:

1982

Langue:

english

Fichier:

PDF, 226 KB

english, 1982

9

Structures of cytochalasin k, l and m, isolated from chalara microspora

Journal:

Tetrahedron Letters

Année:

1981

Langue:

english

Fichier:

PDF, 191 KB

english, 1981

10

A stereospecific synthesis of chaloxone

Journal:

Tetrahedron Letters

Année:

1981

Langue:

english

Fichier:

PDF, 96 KB

english, 1981

11

Synthesis and biological evaluation of reversible inhibitors of IdeS, a bacterial cysteine protease and virulence determinant

Kristina Berggren, Björn Johansson, Tomas Fex, Jan Kihlberg, Lars Björck, Kristina Luthman

Journal:

Bioorganic & Medicinal Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 489 KB

english, 2009

12

Fluorinated linkers for monitoring solid-phase synthesis using gel-phase 19F NMR spectroscopy

Anette Svensson, Karl-Erik Bergquist, Tomas Fex, Jan Kihlberg

Journal:

Tetrahedron Letters

Année:

1998

Langue:

english

Fichier:

PDF, 242 KB

english, 1998

13

Synthesis and Biological Evaluation of New 1,2-Dihydro-4-hydroxy-2-oxo-3-quinolinecarboxamides for Treatment of Autoimmune Disorders: Structure−Activity Relationship

Jönsson, Stig, Andersson, Gunnar, Fex, Tomas, Fristedt, Tomas, Hedlund, Gunnar, Jansson, Karl, Abramo, Lisbeth, Fritzson, Ingela, Pekarski, Olga, Runström, Anna

Journal:

Journal of Medicinal Chemistry

Année:

2004

Langue:

english

Fichier:

PDF, 254 KB

english, 2004

14

Use of 19F NMR spectroscopy to screen chemical libraries for ligands that bind to proteins

Tengel, Tobias, Fex, Tomas, Emten�s, Hans, Almqvist, Fredrik, Sethson, Ingmar, Kihlberg, Jan

Journal:

Organic & Biomolecular Chemistry

Année:

2004

Langue:

english

Fichier:

PDF, 196 KB

english, 2004

15

Design, synthesis and biological evaluation of thrombin inhibitors based on a pyridine scaffold

Blomberg, David, Fex, Tomas, Xue, Yafeng, Brickmann, Kay, Kihlberg, Jan

Journal:

Organic & Biomolecular Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 245 KB

english, 2007

16

A serendipitously identified novel small molecule procoagulant compound giving rise to a high-throughput screening assay based on human plasma

Gustafsson, David, Nielsen, Sofi, McPheat, Jane, Wågberg, Fredrik, Kaspersson, Karin, Rohman, Mattias, Ulander, Johan, Fex, Tomas, Fjellström, Ola, Deinum, Johanna

Journal:

Thrombosis Research

Année:

2013

Langue:

english

Fichier:

PDF, 957 KB

english, 2013

17

Compounds Binding to the S2−S3 Pockets of Thrombin

Nilsson, Mikael, Hämäläinen, Markku, Ivarsson, Maria, Gottfries, Johan, Xue, Yafeng, Hansson, Sebastian, Isaksson, Roland, Fex, Tomas

Journal:

Journal of Medicinal Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 1.56 MB

english, 2009

18

Synthesis and evaluation of diphenylphosphinic amides and diphenylphosphine oxides as inhibitors of Kv1.5

Olsson, Roine I., Jacobson, Ingemar, Boström, Jonas, Fex, Tomas, Björe, Annika, Olsson, Christina, Sundell, Johan, Gran, Ulrik, Öhrn, Anna, Nordin, Andreas, Gyll, Jonna, Thorstensson, Maria, Hayen, Ah

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2013

Langue:

english

Fichier:

PDF, 3.33 MB

english, 2013

19

Discovery of the Fibrinolysis Inhibitor AZD6564, Acting via Interference of a Protein–Protein Interaction

Cheng, Leifeng, Pettersen, Daniel, Ohlsson, Bengt, Schell, Peter, Karle, Michael, Evertsson, Emma, Pahlén, Sara, Jonforsen, Maria, Plowright, Alleyn T., Boström, Jonas, Fex, Tomas, Thelin, Anders, Hil

Journal:

ACS Medicinal Chemistry Letters

Année:

2014

Langue:

english

Fichier:

PDF, 1.62 MB

english, 2014

20

Clavatadine A, A Natural Product with Selective Recognition and Irreversible Inhibition of Factor XIa †

Buchanan, Malcolm S., Carroll, Anthony R., Wessling, Deborah, Jobling, Michael, Avery, Vicky M., Davis, Rohan A., Feng, Yunjiang, Xue, Yafeng, Öster, Linda, Fex, Tomas, Deinum, Johanna, Hooper, John

Journal:

Journal of Medicinal Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 589 KB

english, 2008

21

Preparation of Fluorinated Linkers: Use of 19 F NMR Spectroscopy to Establish Conditions for Solid-Phase Synthesis of Pilicide Libraries

Svensson, Anette, Fex, Tomas, Kihlberg, Jan

Journal:

Journal of Combinatorial Chemistry

Année:

2000

Langue:

english

Fichier:

PDF, 166 KB

english, 2000

22

3-Aminopiperidine-Based Peptide Analogues as the First Selective Noncovalent Inhibitors of the Bacterial Cysteine Protease IdeS

Berggren, Kristina, Vindebro, Reine, Bergström, Claes, Spoerry, Christian, Persson, Helena, Fex, Tomas, Kihlberg, Jan, von Pawel-Rammingen, Ulrich, Luthman, Kristina

Journal:

Journal of Medicinal Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 1.29 MB

english, 2012

23

New Hits as Antagonists of GPR103 Identified by HTS

Nordqvist, Anneli, Kristensson, Lisbeth, Johansson, Kjell E., Isaksson da Silva, Krystle, Fex, Tomas, Tyrchan, Christian, Svensson Henriksson, Anette, Nilsson, Kristina

Journal:

ACS Medicinal Chemistry Letters

Année:

2014

Langue:

english

Fichier:

PDF, 2.01 MB

english, 2014

24

Apolipoproteins A-I and B in Obese Children

Sveger, Tomas, Flodmark, Carl-Erik, Fex, Göran, Henningsen, Nels Christian

Journal:

Journal of Pediatric Gastroenterology & Nutrition

Année:

1989

Fichier:

PDF, 317 KB

1989

25

Apolipoprotein A-I

Sveger, Tomas, Fex, Göran, Flodmark, Carl-Erik, Kjellström, Thomas, Borgfors, Nils

Journal:

Journal of Pediatric Gastroenterology & Nutrition

Année:

1990

Fichier:

PDF, 406 KB

1990

26

Antibody Affinity Against 2009 A/H1N1 Influenza and Pandemrix Vaccine Nucleoproteins Differs Between Childhood Narcolepsy Patients and Controls

Lind, Alexander, Freyhult, Eva, Ramelius, Anita, Olsson, Tomas, Arnheim-Dahlström, Lisen, Lamb, Favelle, Khademi, Mohsen, Ambati, Aditya, Maeurer, Markus, Lima Bomfim, Izaura, Fink, Katharina, Fex, Ma

Journal:

Viral Immunology

Année:

2017

Langue:

english

Fichier:

PDF, 584 KB

english, 2017

27

Plasminogen binding inhibitors demonstrate unwanted activities on GABA A and glycine receptors in human iPSC derived neurons

Kristensson, Lisbeth, Lundin, Anders, Gustafsson, David, Fryklund, Jan, Fex, Tomas, Delsing, Louise, Ryberg, Erik

Journal:

Neuroscience Letters

Année:

2018

Langue:

english

Fichier:

PDF, 1.58 MB

english, 2018